| 货号:21277-1 mg | 规格:1 mg | 目录价:¥375 |
| 货号:21277-10 mg | 规格:10 mg | 目录价:¥1300 |
| 货号:21277-5 mg | 规格:5 mg | 目录价:¥737 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Enasidenib
别名:
AG-221|CC-90007
产品描述:
An inhibitor of mutant IDH2 (IC50 = 0.1 µM for IDH2 R140Q); selective for IDH2 R140Q over wild-type IDH2, wild-type IDH1, and IDH1 R132H (IC50s = 1.8, 0.45, and 48.4 µM, respectively); inhibits production of D-2-hydroxyglutarate and induces differentiation in primary AML cells expressing IDH2 R140Q at 0.1, 1, and 5 µM; increases survival in a PDX mouse model at 5, 15, and 45 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
473.4
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1446502-11-9
分子式:
C19H17F6N7O
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