eNos Antibody / NOS3-多抗-深圳欣博盛生物科技有限公司

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eNos Antibody / NOS3

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：RQ5345

规格：100 ug

目录价：￥6488.05

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

eNos Antibody / NOS3

产品描述:

NOS3 (Nitric Oxide Synthase 3), also called ENOS, anitric oxide synthasethat generatesNOinblood vesselsand is involved with regulatingvascular toneby inhibitingsmooth musclecontraction and plateletaggregation. The NOS3 gene is mapped on 7q36.1. Variations in this gene are associated with susceptibility tocoronary spasm. Fulton et al.(1999) concluded the eNOS is an AKT substrate linking signal transduction by AKT to the release of the gaseous second messenger nitric oxide. AKT mediates the activation of eNOS, leading to increased nitric oxide production. Inhibition of the PI3K AKT pathway or mutation of the AKT site on eNOS protein at serine-1177 attenuated the serine phosphorylation and prevented the activation of eNOS. RT-PCR analysis showed that expression ofNOS3in human umbilical vein endothelial cells (HUVECs) and human aortic vascular smooth muscle cells (HAOVSMCs) was inversely proportional to that of NOS3AS.

反应种属:

Human, Mouse, Rat

宿主来源:

Rabbit

实验应用:

WB, IHC-P, FACS, Direct ELISA

同种型:

Rabbit IgG

免疫原:

Amino acids Q1052-P1203 from the human protein were used as the immunogen for the NOS3 antibody.

克隆性:

Polyclonal (rabbit origin)