深圳欣博盛生物科技有限公司 a1

Enzomenib
货号:44271-1 mg 规格:1 mg 目录价:¥1750
货号:44271-10 mg 规格:10 mg 目录价:¥12250
货号:44271-25 mg 规格:25 mg 目录价:¥24066
货号:44271-5 mg 规格:5 mg 目录价:¥7434
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Enzomenib
别名:
DSP-5336
产品描述:
An inhibitor of the menin-MLL1 protein-protein interaction; binds to menin (Kd = 6 nM) and inhibits the menin-MLL1 interaction (IC50 = 1.4 nM); selectively inhibits the growth of MV4-11, MOLM-13, KOPN-8, and OCI-AML-3 leukemia cells (IC50s = 10, 15, 31, and 15 nM, respectively), which contain MLL-r or NPM1 mutations, over HL-60, MOLT-4, and Reh leukemia cells (IC50s = >10 µM for all), which do not have MLL-r or NPM1 mutations; has antitumor activity in an MV4-11 mouse xenograft model at 25 and 50 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
590.744403
产品形式:
A solid
有效期:
1460
纯度:
≥98%
CAS号:
2412555-70-3
分子式:
C33H43FN6O3
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