| 货号:38427-1 mg | 规格:1 mg | 目录价:¥992 |
| 货号:38427-10 mg | 规格:10 mg | 目录价:¥7839 |
| 货号:38427-5 mg | 规格:5 mg | 目录价:¥4167 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
EP4 Antagonist 14
别名:
PGE2 Receptor 4 Antagonist 14|Prostaglandin E2 Receptor 4 Antagonist 14
产品描述:
An EP4 antagonist (IC50 = 1.1 nM in a reporter assay); inhibits PGE2-induced β-arrestin recruitment in the same cells (IC50 = 0.9 nM); decreases PGE2-induced expression of mRNA encoding Il4, Mrc1, Chil3, Cxcl1, Trem2, and Arg1 in RAW 264.7 macrophages at 10 µM; inhibits tumor growth and increases infiltration of CD8+ T cells into tumors in combination with an anti-PD-1 antibody in a CT26 murine colon cancer model at 30 mg/kg per day
保存温度:
-20
运输温度:
-20
预期分子量:
453.413349
产品形式:
A solid
纯度:
≥95%
CAS号:
3035217-40-1
分子式:
C24H18F3N3O3
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