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折扣/货期| 货号：15214-10 mg | 规格：10 mg | 目录价：￥1300 |
| 货号：15214-25 mg | 规格：25 mg | 目录价：￥2921 |
| 货号：15214-5 mg | 规格：5 mg | 目录价：￥1085 |
| 货号：15214-50 mg | 规格：50 mg | 目录价：￥5293 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Epalrestat
别名:
ONO-2235
产品描述:
An aldose reductase inhibitor (IC50s = 0.01 and 0.26 µM for rat lens and human placenta aldose reductase, respectively); inhibits glucose-induced sorbitol accumulation in isolated rat lens, rat sciatic nerve, and human erythrocytes (IC50s = 1.5, 5, and 1.5 µM, respectively); decreases high glucose-induced proliferation of vascular smooth muscle cells at 10 nM and prevents high glucose-induced intracellular NADH/NAD+ increases and membrane-bound PKC activation at 100 nM; improves motor nerve conduction velocity and decreases sorbitol content in the sciatic nerve and erythrocytes in a rat model of streptozotocin-induced diabetic neuropathy at 20 and 40 mg/kg; prevents capillary strand formation in a rat model of diabetes-induced retinal microangiopathy at 50 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
319.4
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
82159-09-9
分子式:
C15H13NO3S2
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