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折扣/货期| 货号：44442-1 mg | 规格：1 mg | 目录价：￥770 |
| 货号：44442-10 mg | 规格：10 mg | 目录价：￥5390 |
| 货号：44442-25 mg | 规格：25 mg | 目录价：￥8666 |
| 货号：44442-5 mg | 规格：5 mg | 目录价：￥3472 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Epertinib (hydrochloride)
别名:
S-222611
产品描述:
An inhibitor of EGFR, HER2, and HER4 (IC50s = 1.48, 7.15, and 2.49 nM, respectively); selective for these kinases over VEGFR2, IGF-1R, c-Src, KIT, and PDGFRβ (IC50s = >10,000 nM for all); inhibits EGFR and HER2 autophosphorylation in NCI N87 cells (IC50s = 4.5 and 1.6 nM, respectively); selectively inhibits the growth of NCI N87, BT474, and HT115 cancer cell lines (IC50s = 8.3, 9.9, and 53.3 nM, respectively) over fR2 cells and MRC-5 fibroblasts (IC50s = 5,366.7 and 4,964.6 nM, respectively); decreases tumor volume in an NCI N87 mouse xenograft model at 12.5 or 50 mg/kg per day
保存温度:
-20
运输温度:
-20
预期分子量:
560.026403
产品形式:
A solid
有效期:
1460
纯度:
≥98%
CAS号:
2071195-74-7
分子式:
C30H27ClFN5O3 • HCl
促销活动
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