| 货号:18136-10 mg | 规格:10 mg | 目录价:¥495.8 |
| 货号:18136-100 mg | 规格:100 mg | 目录价:¥2117.2 |
| 货号:18136-50 mg | 规格:50 mg | 目录价:¥1420.4 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Epinastine (hydrochloride)
别名:
WAL 801CL
产品描述:
A histamine H1 receptor antagonist (apparent Kis = 1.41 and 1.62 nM using guinea pig cerebellar and lung membranes, respectively) and mast cell stabilizer; inhibits IgE-induced histamine, TNF-α, and IL-10 secretion in human CBMCs at 0.1 μg/ml; inhibits histamine-induced cutaneous vascular permeability in rats and bronchoconstriction in anesthetized guinea pigs (ID50s = 5 and 0.1 mg/kg, respectively); inhibits dye leakage into the conjunctiva in a rat model of passive anaphylaxis reaction-induced vascular hyperpermeability of the conjunctiva (ID50 = 9.7 mg/kg, p.o.); topical administration reduces lid edema, tearing, and redness, as well as the number of neutrophils and eosinophils in the lid fornix, in a mouse model of atopic conjunctivitis
保存温度:
-20
运输温度:
-20
预期分子量:
285.8
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
108929-04-0
分子式:
C16H15N3 • HCl
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