官网链接
折扣/货期| 货号：16174-1 mg | 规格：1 mg | 目录价：￥482 |
| 货号：16174-10 mg | 规格：10 mg | 目录价：￥951 |
| 货号：16174-5 mg | 规格：5 mg | 目录价：￥710 |
| 货号：16174-50 mg | 规格：50 mg | 目录价：￥3538 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
EPZ6438
别名:
Tazemetostat
产品描述:
An EZH2 inhibitor (IC50 = 11 nM); inhibits mutant EZH2, including EZH2A677G, EZH2A687V, and EZH2Y641F, and EZH2Y641S (IC50s = 2, 2, 14, and 4 nM, respectively); selective for wild-type and mutant EZH2 over EZH1 (IC50 = 392 nM) and a variety of other histone methyltransferases (IC50s = >50 or >100 µM for all); reduces H3K27me3 levels in various lymphoma cell lines expressing wild-type or mutant EZH2 (IC50s = 2-8 and 2-22 nM, respectively); inhibits proliferation of various lymphoma cell lines expressing wild-type or mutant EZH2 (IC50s = 0.099-6.2 and 0.00049-5.8 µM, respectively); induces insulin production and glucose-stimulated insulin secretion in human pancreatic exocrine cells isolated from juvenile patients with type 1 diabetes or adults without diabetes at 1 µM; reduces H3K27me3 levels and induces insulin secretion and glucose-stimulated insulin secretion in human pancreatic ductal epithelial cells in vitro
保存温度:
-20
运输温度:
-20
预期分子量:
572.7
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1403254-99-8
分子式:
C34H44N4O4
促销活动
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