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折扣/货期| 货号：24104-1 mg | 规格：1 mg | 目录价：￥482 |
| 货号：24104-10 mg | 规格：10 mg | 目录价：￥1608 |
| 货号：24104-25 mg | 规格：25 mg | 目录价：￥3390 |
| 货号：24104-5 mg | 规格：5 mg | 目录价：￥938 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
ETC-159
别名:
ETC-1922159
产品描述:
A potent, orally bioavailable inhibitor of PORCN (IC50s = 18.1 and 70 nM for mouse and Xenopus PORCN, respectively); inhibits β-catenin reporter activity (IC50 = 2.9 nM) and reduces the interaction of Wnt with its carrier protein WLS via decreased Wnt palmitoleation in STF3A cells; inhibits PA-1 teratocarcinoma colony formation in soft agar (IC50 = 35 nM); reduces tumor growth in a dose-dependent manner in mice carrying a mouse mammary tumor virus LTR-Wnt1 transgene and in A-1 and NCCIT teratocarcinoma mouse xenograft models (1-10 mg/kg); reduces growth and induces differentiation in colon adenocarcinoma mouse xenograft models that contain RSPO translocations
保存温度:
-20
运输温度:
-20
产品形式:
A crystalline solid
纯度:
≥95%
CAS号:
1638250-96-0
分子式:
C19H17N7O3
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