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折扣/货期| 货号：FY12008 | 规格：100 ul | 目录价：￥6488.05 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
EXOC2 Antibody / Exocyst complex component 2
产品描述:
EXOC2 antibody detects exocyst complex component 2, a critical member of the octameric exocyst complex that regulates tethering of secretory vesicles to the plasma membrane. This protein, also known as Sec5, functions in exocytosis and polarized trafficking, ensuring cargo delivery to specific membrane domains. By organizing vesicle docking, EXOC2 plays a fundamental role in processes such as cell migration, epithelial polarity, and neurite outgrowth. Its interactions with Ral GTPases highlight its role in small GTPase-mediated trafficking control.
Research using EXOC2 antibody has connected this protein to cancer and neurological disorders. Overexpression of EXOC2 has been reported in several tumor types, where it may promote invasive behavior by enhancing targeted membrane addition and secretion of proteases. In neurons, altered exocyst function has been linked to impaired synaptic vesicle recycling and neurodevelopmental defects. Investigating EXOC2 therefore provides insight into both normal cellular organization and disease pathology.
Antibodies against EXOC2 have been validated in western blot, immunohistochemistry, and immunoprecipitation. These tools help characterize exocyst assembly, subcellular localization, and interactions with signaling proteins. High-specificity clones are particularly valuable for distinguishing EXOC2 from related exocyst components within large multiprotein complexes.
NSJ Bioreagents supplies this EXOC2 antibody for research applications in membrane trafficking, cancer biology, and neurobiology. Alternate names include exocyst complex component 2 antibody, Sec5 antibody, SEC5L1 antibody, and Sec5p antibody.
Research using EXOC2 antibody has connected this protein to cancer and neurological disorders. Overexpression of EXOC2 has been reported in several tumor types, where it may promote invasive behavior by enhancing targeted membrane addition and secretion of proteases. In neurons, altered exocyst function has been linked to impaired synaptic vesicle recycling and neurodevelopmental defects. Investigating EXOC2 therefore provides insight into both normal cellular organization and disease pathology.
Antibodies against EXOC2 have been validated in western blot, immunohistochemistry, and immunoprecipitation. These tools help characterize exocyst assembly, subcellular localization, and interactions with signaling proteins. High-specificity clones are particularly valuable for distinguishing EXOC2 from related exocyst components within large multiprotein complexes.
NSJ Bioreagents supplies this EXOC2 antibody for research applications in membrane trafficking, cancer biology, and neurobiology. Alternate names include exocyst complex component 2 antibody, Sec5 antibody, SEC5L1 antibody, and Sec5p antibody.
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
WB
同种型:
Rabbit IgG
免疫原:
A synthesized peptide derived from human EXOC2 was used as the immunogen for the EXOC2 antibody.
克隆性:
Recombinant Rabbit Monoclonal
克隆号:
31E49
纯化方式:
Affinity-chromatography
保存温度:
Store the EXOC2 antibody at -20oC.
产品形式:
Liquid
存储溶液:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
产地:
美国
上一个:CLIC4 Antibody / Chloride intracellular channel protein 4
下一个:BCL2L15 Antibody / BCL2 like protein 15
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