EZH2 Antibody-多抗-深圳欣博盛生物科技有限公司

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EZH2 Antibody

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：F53753-0.4ML	规格：0.4 ml	目录价：￥6344
货号：F53753-0.08ML	规格：0.08 ml	目录价：￥2962

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

EZH2 Antibody

产品描述:

EZH2, SUZ12, and EED form a complex that methylates nucleosomal histone H3 at Lys27. EZH2 contains a SET domain, a signature motif for all known histone lysine methyltransferases except the H3-K79 methyltransferase DOT1, and is therefore likely to be the catalytic subunit. Consequently, EZH2 is thought to regulate gene expression by controlling chromatin structure. Several lines of evidence suggested a critical role for the EZH2 protein during normal and perturbed development of the hematopoietic and central nervous systems. The EZH2 protein has been shown to associate with the VAV1 protooncoprotein and with the XNP protein, the product of a gene associated with mental retardation. Additionally, due to mapping of EZH2 to the 7q35-q36 chromosomal region associated with myeloid disorders, this protein is suggested to participate in the genetic events triggering myeloid leukemia.

反应种属:

Human, Mouse, Rat

宿主来源:

Rabbit

实验应用:

WB, IHC, ELISA

同种型:

Rabbit Ig

免疫原:

This EZH2 antibody was produced from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human EZH2.

克隆性:

Polyclonal (rabbit origin)