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折扣/货期| 货号：29954-1 mg | 规格：1 mg | 目录价：￥1005 |
| 货号：29954-10 mg | 规格：10 mg | 目录价：￥8871 |
| 货号：29954-5 mg | 规格：5 mg | 目录价：￥4703 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
EZM2302
别名:
GSK3359088
产品描述:
A PRMT4 inhibitor (IC50 = 6 nM); decreases asymmetric methylation of PABP1 (IC50 = 0.038 µM) and increases levels of demethylated SmB (EC50 = 0.018 µM) in RPMI-8226 multiple myeloma cells; inhibits proliferation in a panel of 36 hematopoietic cancer cell lines (IC50s = <100 µM for 9 out of 15 multiple myeloma cell lines); reduces tumor growth and decreases asymmetric PABP1 methylation in tumor tissue in an RPMI-8226 mouse xenograft model at 75, 150, and 300 mg/kg twice per day; reduces acute mechanical allodynia and thermal hyperalgesia in a mouse model of CCI-induced neuropathic pain at 10 µg
保存温度:
-20
运输温度:
-20
预期分子量:
585.09422
产品形式:
A solid
纯度:
≥98%
CAS号:
1628830-21-6
分子式:
C29H37ClN6O5
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