深圳欣博盛生物科技有限公司 a1

FA16
货号:40499-1 mg 规格:1 mg 目录价:¥429
货号:40499-10 mg 规格:10 mg 目录价:¥3002
货号:40499-25 mg 规格:25 mg 目录价:¥6419
货号:40499-5 mg 规格:5 mg 目录价:¥1608
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
FA16
产品描述:
A ferroptosis inducer and an inhibitor of the system xc- cystine/glutamate transporter; reduces viability of various cancer cell lines (IC50s = 0.7-4.34 µM); FA16-induced death of HT-1080 cells can be blocked by ferrostatin-1, Trolox, DFO, and β-mercaptoethanol and potentiated by exogenous iron; increases ROS production in HT-1080 cells at 5 µM, which can be blocked by ferrostatin-1; inhibits glutamate release from HT-1080 cells; reduces tumor growth and increases intratumoral levels of 4-HNE and MDA in a HepG2 mouse xenograft model at 15 and 30 mg/kg; has an increased half-life and slower clearance than erastin in human and rat liver microsomes
保存温度:
-20
运输温度:
-20
预期分子量:
466.520869
产品形式:
A solid
纯度:
≥95%
CAS号:
3037775-42-8
分子式:
C22H25F3N4O2S
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