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折扣/货期| 货号：60-625 | 规格：400 ul | 目录价：￥8687.25 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
FADD Antibody
别名:
FAS-associated death domain protein, FAS-associating death domain-containing protein, Growth-inhibiting gene 3 protein, Mediator of receptor induced toxicity, Protein FADD, FADD, MORT1
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB
同种型:
Rabbit Ig
克隆性:
Polyclonal
纯化方式:
This antibody is purified through a protein A column, followed by peptide affinity purification.
偶联:
Unconjugated
产品浓度:
batch dependent
保存温度:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
Supplied in PBS with 0.09% (W/V) sodium azide.
产地:
美国
生产商:
Prosci
功能与背景:
The protein encoded by this gene is an adaptor molecule
that interacts with various cell surface receptors and mediates
cell apoptotic signals. Through its C-terminal death domain, this
protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis
factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it
participates in the death signaling initiated by these receptors.
Interaction of this protein with the receptors unmasks the
N-terminal effector domain of this protein, which allows it to
recruit caspase-8, and thereby activate the cysteine protease
cascade. Knockout studies in mice also suggest the importance of
this protein in early T cell development.
Accession #:
Q13158
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