| 货号:R31346 | 规格:100 ug | 目录价:¥6488.05 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
FAT10 Antibody / Ubiquitin D / UBD
产品描述:
Ubiquitin D, Diubiquitin or FAT10 (HLA-F-adjacent transcript 10), is a protein that in humans is encoded by the UBD gene. It is a ubiquitin-like protein modifier that can be covalently attached to target protein and subsequently leads to their degradation by the 26S proteasome in a NUB1L-dependent manner. This gene may be involved in dendritic cell (DC) maturation, the process by which immature dendritic cells differentiate into fully competent antigen-presenting cells that initiate T-cell responses. It may be involved in the formation of aggresomes when proteasome is saturated or impaired. FAT10 mediates apoptosis in a caspase-dependent manner, especially in renal epithelium and tubular cells during renal diseases such as polycystic kidney disease and Human immunodeficiency virus (HIV)-associated nephropathy (HIVAN). It may also function as a survival factor.
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB, IHC-P
同种型:
Rabbit IgG
免疫原:
An amino acid sequence from the N-terminus of human HLA-F-adjacent transcript 10 (YDSVKKIKEHVRSK) was used as the immunogen for this FAT10 antibody.
克隆性:
Polyclonal (rabbit origin)
纯化方式:
Antigen affinity
保存温度:
After reconstitution, the FAT10 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
产品形式:
Antigen affinity purified
存储溶液:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
产地:
美国
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