深圳欣博盛生物科技有限公司 a1

Fenebrutinib
货号:21346-1 mg 规格:1 mg 目录价:¥375
货号:21346-10 mg 规格:10 mg 目录价:¥2211
货号:21346-25 mg 规格:25 mg 目录价:¥4154
货号:21346-5 mg 规格:5 mg 目录价:¥1206
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Fenebrutinib
别名:
GDC-0853|RG-7845
产品描述:
A BTK inhibitor (Kis = 0.91, 1.6, 1.3, 12.6, and 3.4 nM for wild-type BTK, BTKC481S, BTKC481R, BTKT474I, and BTKT474M, respectively); selective for BTK over a panel of 287 additional kinases at 1 µM; inhibits anti-IgM antibody-induced BTK phosphorylation in B cells (IC50 = 3.1 nM), as well as anti-IgM- or CD40L-induced proliferation of B cells (IC50s = 1.2 and 1.4 nM, respectively); reduces ankle thickness and cartilage damage in a rat model of collagen-induced arthritis
保存温度:
-20
运输温度:
-20
预期分子量:
664.8
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1434048-34-6
分子式:
C37H44N8O4
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