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折扣/货期| 货号：17688-100 mg | 规格：100 mg | 目录价：￥2600 |
| 货号：17688-50 mg | 规格：50 mg | 目录价：￥1380 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Fenretinide
别名:
4-HPR|4-Hydroxy(phenyl)retinamide|MK-4016|Retinoic Acid p-hydroxyphenylamide|Ro 22-4667
产品描述:
An inhibitor of dihydroceramide desaturase (IC50 = 2.32 µM); promotes the generation of ROS, degradation of MCL-1, and cleavage of PKCδ; selectively activates RARγ at 5-20 µM; inhibits the growth of Caov-3, OVCAR-3, and SKOV3 ovarian cancer cells (IC50s = 3.7, 6.9, and 8.2 µM, respectively); increases activity of SPT by 1.75-fold and induces caspase-dependent apoptosis in BMEC cells (IC50 = 2.4 µM); prevents lipid-induced reductions in insulin-stimulated glucose uptake in isolated rat soleus muscle; reduces liver and soleus muscle neutral lipid content and inhibits high-fat diet-induced increases in dihydroceramide desaturase transcription at 10 mg/ml
保存温度:
-20
运输温度:
-20
预期分子量:
391.6
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
65646-68-6
分子式:
C26H33NO2
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