深圳欣博盛生物科技有限公司 a1

FGTI-2734
货号:37694-1 mg 规格:1 mg 目录价:¥389
货号:37694-10 mg 规格:10 mg 目录价:¥3015
货号:37694-25 mg 规格:25 mg 目录价:¥6593
货号:37694-5 mg 规格:5 mg 目录价:¥1715
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
FGTI-2734
产品描述:
A dual inhibitor of FTase and GGTase I (IC50s = 250 and 520 nM, respectively); inhibits prenylation of H-Ras and Rap1A (IC50s = 88.7 and 2,700 nM, respectively) in oncogenic H-Ras-transformed NIH3T3 cells; inhibits membrane localization of K-Ras in MIA PaCa-2 and H460 cancer cells at 10 and 30 µM; reduces tumor growth, increases intratumoral expression of p53, induces intratumoral apoptosis, and decreases intratumoral HDJ2 farnesylation and Rap1A geranylgeranylation in PDX mouse models of mutant KRAS-expressing pancreatic cancer at 50 and 100 mg/kg per day
保存温度:
-20
运输温度:
-20
预期分子量:
510.627983
产品形式:
A solid
纯度:
≥95%
CAS号:
1247018-19-4
分子式:
C26H31FN6O2S
在线留言
咨询类型
联系人
*
联系方式
*
单位名称
*
咨询内容
*
复制QQ号成功,请打开QQ后添加好友进行咨询