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折扣/货期| 货号：13943-10 mg | 规格：10 mg | 目录价：￥3390 |
| 货号：13943-25 mg | 规格：25 mg | 目录价：￥7571 |
| 货号：13943-5 mg | 规格：5 mg | 目录价：￥1796 |
| 货号：13943-50 mg | 规格：50 mg | 目录价：￥12408 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
FKGK 18
产品描述:
An inhibitor of GVIA iPLA2; inhibits GVIA iPLA2 by 99.9% at 0.091 mol fraction in a mixed micelle activity assay; is selective for GVIA iPLA2 over GIVA cPLA2 and GV sPLA2 where it shows 80.8 and 36.8% inhibition, respectively; inhibits iPLA2β activity in cytosolic extracts from INS-1 cells overexpressing iPLA2β (IC50 = ~50 nM) as well as iPLA2γ activity in mouse heart membrane fractions (IC50 = ~1-3 μM); inhibits glucose-induced increases in PGE2 production and insulin secretion in human pancreatic islets at 10 μM; inhibits thapsigargin-induced apoptosis in INS-1 cells overexpressing iPLA2β in a concentration-dependent manner; reduces blood glucose levels in an intraperitoneal glucose tolerance test and incidence of diabetes and increases serum insulin levels in NOD mice at 20 mg/kg, 3 times per week
保存温度:
-20
运输温度:
-20
预期分子量:
280.3
产品形式:
A crystalline solid
纯度:
≥95%
CAS号:
1071001-09-6
分子式:
C16H15F3O
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