深圳欣博盛生物科技有限公司 a1

Flavopiridol
货号:26024-100 mg 规格:100 mg 目录价:¥9675
货号:26024-25 mg 规格:25 mg 目录价:¥3069
货号:26024-5 mg 规格:5 mg 目录价:¥844
货号:26024-50 mg 规格:50 mg 目录价:¥5668
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Flavopiridol
别名:
Alvocidib|HL 275|HMR 1275|L-868,275
产品描述:
An inhibitor of cyclin-dependent kinases (Cdks; IC50s = ~100, ~100, ~100, and 300 nM for Cdk1, Cdk2, Cdk4, and Cdk7, respectively); inhibits TEFb (Ki = 3 nM); inhibits transcription of a CMV promoter in HeLa nuclear extract (IC50 = 34 nM), Tat-stimulated transcription of an HIV-1 promotor (IC50 = 7 nM), and HIV-1 replication in HEK293T cells (IC50 = <10 nM); induces apoptosis and cyclin D1 depletion and delays tumor growth in an HN-12 head and neck carcinoma mouse xenograft model at 5 mg/kg; suppresses synovial hyperplasia and joint destruction in a mouse model of collagen-induced arthritis
保存温度:
-20
运输温度:
-20
预期分子量:
401.83994
产品形式:
A crystalline solid
纯度:
≥95%
CAS号:
146426-40-6
分子式:
C21H20ClNO5
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