FLT3 Ligand (human) (rec.) (His)-其他重组蛋白-深圳欣博盛生物科技有限公司

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FLT3 Ligand (human) (rec.) (His)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：CHI-HF-201FLT3L-C010

规格：10 ug

目录价：￥2940

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

FLT3 Ligand (human) (rec.) (His)

别名:

FLT3L; FMS-like Tyrosine Kinase 3 Ligand

产品描述:

FMS-like tyrosine kinase 3 ligand (FLT3L) acts as a growth factor that increases the number of immune cells (lymphocytes (B cells and T cells)) by activating the hematopoietic progenitors. It binds to FLT3 (CD135) which is found on multipotent progenitor (MPP) and common lymphoid progenitor (CLP) cells in mice. FLT3L induces the mobilization of the hematopoietic progenitors and stem cells in vivo which may help the system to kill cancer cells. FLT3L is crucial for steady-state pDC (plasmacytoid dendritic cells) and cDC (classical dendritic cells) development. Deficiency of FLT3L causes a dramatic decrease in DC numbers, whereas increasing its availability increase in DC numbers.

宿主来源:

HEK 293 cells

保存温度:

+4°C

运输温度:

预期分子量:

~25kDa (SDS-PAGE)

产品形式:

solid

存储溶液:

Lyophilized from 0.2µm-filtered solution in PBS.

产地:

瑞士

纯度:

>95% (SDS-PAGE)

生物活性:

The ED50 was determined by the dose-dependent stimulation of the proliferation of human AML5 cells is < 1.0 ng/ml, corresponding to a specific activity of > 1 x 106 units/mg.

内毒素水平:

<0.001EU/µg purified protein (LAL test; Lonza).

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