官网链接
折扣/货期| 货号：CDX-F0141-M010 | 规格：10 mg | 目录价：￥364 |
| 货号：CDX-F0141-M050 | 规格：50 mg | 目录价：￥924 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Fluoxetine hydrochloride
别名:
(±)-N-Methyl-gamma-[4-(trifluoromethyl)phenoxy]benzenepropanamine hydrochloride; LY-110,140 hydrochloride; Prozac
产品描述:
Fluoxetine is a cell-permeable selective serotonin reuptake inhibitor (SSRI), with preference for the serotonin transporter (Kd=0.81nM) over the norepinephrine transporter (Kd=240nM) and the dopamine transporter (Kd=3600nM). This drug works at presynaptic terminals where it prevents the reuptake of serotonin, resulting in the accumulation of serotonin in extracellular fluid at synapses. It functions as an antidepressant. Fluoxetine binds also to the human 5-HT transporter and is between 150- and 900- fold selective over 5-HT1A, 5-HT2A, H1, alpha1, alpha2-adrenergic, and muscarinic receptors. It has been shown to induce differentiation of neuronal precursors, enhancing neuronal characteristics. In addition, it was reported to modulate the proliferation of T-cells by increasing the Ca2+ influx and thereby influencing the activities of protein kinase A (PKA) and protein kinase C (PKC) and to regulate the phosphorylation of DARPP-32 and AMPA receptors.
宿主来源:
Synthetic.
保存温度:
+20°C
运输温度:
Ambient
预期分子量:
345.79
产品形式:
solid
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
56296-78-7
分子式:
C17H18F3NO . HCl
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