深圳欣博盛生物科技有限公司 a1

Fluticasone Propionate
货号:20703-1 mg 规格:1 mg 目录价:¥询价
货号:20703-10 mg 规格:10 mg 目录价:¥询价
货号:20703-25 mg 规格:25 mg 目录价:¥询价
货号:20703-5 mg 规格:5 mg 目录价:¥询价
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Fluticasone Propionate
别名:
Fluticasone 17-Propionate
产品描述:
A synthetic corticosteroid and glucocorticoid receptor agonist; inhibits AP-1-mediated transcription in a transrepression assay using ChaGo-K-1 cells (IC50 = 0.04 nM); selectively binds to the glucocorticoid receptor (IC50 = 0.0009 µM) over the progesterone, mineralocorticoid, and androgen receptors (IC50s = 0.021, 0.149, and >10 µM, respectively), as well as ERα and ERβ (IC50s = >10 µM for both); increases apoptosis of T cells isolated from human peripheral blood and induces spontaneous apoptosis of primary human eosinophils (EC50 = 3.7 nM); completely inhibits congestion in a guinea pig model of ovalbumin-induced allergic rhinitis when administered as a 0.5 mg/ml solution at 20 µl/nostril; reduces ovalbumin-induced increases in IL-4 in nasal lavage fluid in the same model; potentiates Kv1 currents in an inside-out patch-clamp assay (EC50 = 37 nM)
保存温度:
-20
运输温度:
-20
预期分子量:
500.6
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
80474-14-2
分子式:
C25H31F3O5S
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