深圳欣博盛生物科技有限公司 a1

Fruquintinib
货号:29425-10 mg 规格:10 mg 目录价:¥737
货号:29425-100 mg 规格:100 mg 目录价:¥5735
货号:29425-250 mg 规格:250 mg 目录价:¥12516
货号:29425-50 mg 规格:50 mg 目录价:¥3243
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Fruquintinib
别名:
HMPL-013
产品描述:
A VEGFR inhibitor (IC50s = 33, 35, and 0.5 nM for VEGFR1, -2, and -3, respectively); inhibits RET, FGFR1, and c-Kit (IC50s = 128, 181, and 458 nM, respectively) in a panel of 253 kinases; inhibits VEGF-A- induced proliferation of HUVECs and VEGF-C-induced proliferation of HLECs (IC50s = 1.7 and 4.2 nM, respectively); decreases tube formation by HUVECs by 74 and 94% at 30 and 300 nM, respectively; reduces tumor growth in BGC-823, HT-29, Caki-1, and NCI H460 mouse xenograft models at 0.5-20 mg/kg per day for 21 days
保存温度:
-20
运输温度:
-20
预期分子量:
393.39278
产品形式:
A solid
纯度:
≥98%
CAS号:
1194506-26-7
分子式:
C21H19N3O5
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