FSL-1 (trifluoroacetate salt)-激动剂-深圳欣博盛生物科技有限公司

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FSL-1 (trifluoroacetate salt)

品牌：Cayman

官网链接

说明书

折扣/货期

货号：24220-1 mg	规格：1 mg	目录价：￥2720
货号：24220-5 mg	规格：5 mg	目录价：￥9219
货号：24220-500 µg	规格：500 µg	目录价：￥1434

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

FSL-1 (trifluoroacetate salt)

产品描述:

A synthetic lipopeptide agonist of TLR2/TLR6; increases NF-κB activity by 4- and 8-fold in HEK293 cells transfected with TLR2 and TLR6 but not TLR6 alone at 0.1 and 1 nM, respectively; induces the expression of the CCL20, IL-8, IL-1β, and TNF-α in THP-1 cells and, to a lesser extent, in TLR10 knockdown cells at 100 ng/ml; dose-dependently increases the percentage of DM13 and VMM1 melanoma cells expressing CXCL10 when administered in combination with IFN-γ with a maximal increase of 50% at 0.5-50 μg/ml; induces fever and increases plasma levels of IL-6 and TNF-α by greater than 90-fold in rats at 100 μg/kg, i.p.; dose-dependently reduces locomotor activity and both food and water consumption with a maximal reduction of ten grams per 12 hours at 10-1,000 μg/kg, i.p.

保存温度:

-20

运输温度:

-20

预期分子量:

1666.15996

产品形式:

A solid

纯度:

≥95%

分子式:

C84H140N14O18S • XCF3COOH