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折扣/货期| 货号：39275-10 mg | 规格：10 mg | 目录价：￥4194 |
| 货号：39275-5 mg | 规格：5 mg | 目录价：￥2787 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Fumarate hydratase-IN-1
别名:
Fumarate hydratase Inhibitor 1
产品描述:
An antiproliferative and anti-inflammatory compound; inhibits proliferation of, and induces ATP depletion in, SW620, ACHN, HCT116, PC3, and SK-MEL-28 cancer cells in the absence, but not in the presence, of glucose in a concentration-dependent manner; reduces the OCR in SW620 cells in the absence of glucose (IC50 = 2.2 µM); preincubation reduces the secreted levels of Ifn-γ, Tnf-α, and granzyme B from mouse CD8+ T cells when cocultured with B16-OVA cells expressing ovalbumin at 25 µM; increases tumor interstitial fluid levels of fumarate, the percentage of apoptotic tumor-associated CD8+ T cells, reduces the levels of tumor-associated CD44+ CD8+ T cells, as well as decreases survival in a B16-OVA murine melanoma model at 25 mg/kg per day
保存温度:
-20
运输温度:
-20
预期分子量:
446.53818
产品形式:
A solid
纯度:
≥98%
CAS号:
1644060-37-6
分子式:
C27H30N2O4
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