| 货号:37414-1 mg | 规格:1 mg | 目录价:¥964.8 |
| 货号:37414-10 mg | 规格:10 mg | 目录价:¥5279.6 |
| 货号:37414-5 mg | 规格:5 mg | 目录价:¥3363.4 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
G0-C14
产品描述:
An ionizable cationic lipid; has been used in the generation of LNPs for the delivery of siRNA and mRNA in vitro and in vivo; LNPs containing G0-C14 and encapsulating siRNA targeting CaMKIIγ increase plaque stability and promote macrophage efferocytosis of apoptotic cells within plaques in a fat-fed Ldlr-/- mouse model of atherosclerosis; LNPs containing G0-C14 and encapsulating siRNA targeting IL11 reduce fibrosis in a mouse model of bleomycin-induced pulmonary fibrosis when administered via inhalation; LNPs containing G0-C14 and conjugated to eGLP-1selectively accumulate in the pancreas in mice; eGLP-1-conjugated, G0-C14-containing LNPs encapsulating CD274 mRNA induce PD-L1 expression and localization to the pancreatic β cell surface and decrease severe insulitis in mice
保存温度:
-20
运输温度:
-20
预期分子量:
1790.91064
产品形式:
A solid
有效期:
1460
纯度:
≥90%
CAS号:
1510653-27-6
分子式:
C106H216N10O10
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