深圳欣博盛生物科技有限公司 a1

Gambogic Acid
货号:14761-1 mg 规格:1 mg 目录价:¥496
货号:14761-10 mg 规格:10 mg 目录价:¥1863
货号:14761-25 mg 规格:25 mg 目录价:¥2801
货号:14761-5 mg 规格:5 mg 目录价:¥1313
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Gambogic Acid
别名:
GA|β-Guttiferin
产品描述:
A xanthonoid with anticancer activity; binds covalently to SPTSSB (Ki = 1.5 µM; kinact = 0.05 min-1) and inhibits de novo sphingolipid biosynthesis; activates caspases in T47D breast cancer cells (EC50 = 0.78 µM); inhibits binding of anti-apoptotic proteins to a BH3 peptide (IC50s = 1.47, 1.21, 2.02, 0.66, 1.06, and 0.79 μM for Bcl-xL, Bcl-2, Bcl-W, Bcl-B, Bfl-1, Mcl-1, respectively); binds to the transferrin receptor (IC50 = 4.1 µM); reduces growth of a variety of cancer cell lines (GI50s = 0.115-1 µM) and induces apoptosis in T47D cells; a slow inhibitor of inward-rectifying potassium channel 2.1 (Kir2.1; IC50 = <0.1 µM)
保存温度:
-20
运输温度:
-20
预期分子量:
628.8
产品形式:
A crystalline solid
纯度:
≥95% (mixture of epimers)
CAS号:
2752-65-0
分子式:
C38H44O8
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