官网链接
折扣/货期| 货号：39749-1 mg | 规格：1 mg | 目录价：￥3850 |
| 货号：39749-5 mg | 规格：5 mg | 目录价：￥8666 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Gelsevirine
产品描述:
An oxindole alkaloid with anti-inflammatory activity; binds to STING (Kd = 27.6 µM) and prevents 2'3'-cGAMP-induced Sting dimerization in RAW 264.7 cells at 5 µM; inhibits 2'3'-cGAMP-, poly(dA:dT) dsDNA-, or IFN-stimulatory DNA-induced increases in the levels of mRNA encoding CXCL10 and IL-6 in THP-1 monocytes and RAW 264.7 cells at 10 µM; inhibits 2'3'-cGAMP-induced increases in the levels of Sting and phosphorylated IRF3, p65, and TBK1 in RAW 264.7 cells at 5 µM; increases animal survival time, reduces lung injury and total protein levels in BALF, and decreases serum levels of ALT, AST, creatinine, IL-6, TNF-α, and BUN levels in a mouse model of sepsis induced by CLP at 20 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
352.42694
产品形式:
A solid
有效期:
1460
纯度:
≥98%
来源:
Plant/Gelsemium elegans
CAS号:
38990-03-3
分子式:
C21H24N2O3
促销活动
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