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折扣/货期| 货号：36016-10 mg | 规格：10 mg | 目录价：￥1367 |
| 货号：36016-100 mg | 规格：100 mg | 目录价：￥7450 |
| 货号：36016-5 mg | 规格：5 mg | 目录价：￥764 |
| 货号：36016-50 mg | 规格：50 mg | 目录价：￥5226 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Gemigliptin (tartrate)
产品描述:
A DPP-4 inhibitor (IC50 = 0.01 µM); selective for DPP-4 over DPP-8, DPP-9, and FAP- α (IC50s = 277.28, 233.72, 418.43 µM, respectively); inhibits DPP-4 activity in isolated human plasma (IC50 = 11.5 nM); scavenges methylglyoxal in vitro and inhibits AGE formation between BSA and methylglyoxal and cross-linking of AGE-BSA with rat tail tendon collagen (IC50s = 1.15, 11.69, and 1.39 mM, respectively); reduces the levels of circulating AGE and red blood cell IgG content in db/db diabetic mice at 100 mg/kg; decreases blood glucose and HbA1c levels and reduces pancreatic β-cell damage in a mouse model of STZ- and high-fat diet-induced diabetes; induces cytotoxicity in SW1736 and TPC-1 cells
保存温度:
-20
运输温度:
-20
预期分子量:
489.363185
产品形式:
A solid
纯度:
≥98%
CAS号:
1374639-74-3
分子式:
C18H19F8N5O2 • XC4H6O6
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