| 货号:15-309 | 规格:100 uL | 目录价:¥7651.8 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
GLP1R Antibody
别名:
Glp1r, glucagon-like peptide 1 receptor, GLP-1R, GLP1Rc, GLP-1 receptor, GLP-1-R
反应种属:
Human,Rat
宿主来源:
Rabbit
实验应用:
WB,IHC
同种型:
IgG
克隆性:
Polyclonal
纯化方式:
Affinity purification
偶联:
Unconjugated
产品浓度:
batch dependent
保存温度:
Store at -20˚C. Avoid freeze / thaw cycles.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
产地:
美国
生产商:
Prosci
功能与背景:
This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants.

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