| 货号:R31618 | 规格:100 ug | 目录价:¥6488.05 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
GLUR2 Antibody / Glutamate Receptor 2 / GRIA2
产品描述:
Glutamate receptor 2, also known as GLUR2, is a protein that in humans is encoded by the GRIA2 gene. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. The crystal structures of the GLUR2 ligand-binding core in the apo state and in the presence of the antagonist DNQX, the partial agonist kainate, and the full agonists AMPA and glutamate. GLUR2 plays a major role in depression at synapses in which glutamate remains in the synaptic cleft for prolonged periods of time during normal operation of the synapse. Overexpression increases dendritic spine size and density in hippocampal neurons, and more remarkably, induces spine formation in GABA-releasing interneurons that normally lack spines.
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
WB, IHC-P, IF, FACS
同种型:
Rabbit IgG
免疫原:
Human partial recombinant protein (AA 25-360) was used as the immunogen for this GLUR2 antibody.
克隆性:
Polyclonal (rabbit origin)
纯化方式:
Antigen affinity
保存温度:
After reconstitution, the GLUR2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
产品形式:
Antigen affinity purified
存储溶液:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
产地:
美国
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