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折扣/货期| 货号：9003230-1 mg | 规格：1 mg | 目录价：￥1728.6 |
| 货号：9003230-10 mg | 规格：10 mg | 目录价：￥11055 |
| 货号：9003230-5 mg | 规格：5 mg | 目录价：￥5963 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Glycine-β-muricholic Acid
别名:
Gly-MCA|GβMCA
产品描述:
An intestine-selective FXR antagonist; glycine-conjugated form of β-muricholic acid; inhibits chenodeoxycholic acid- and GW 4064-induced expression of the FXR target genes Shp and Fgf15 at 100 μM; resistant to hydrolysis by fecal BSH isolated from gut microbiota; decreases Shp and Fgf15 mRNA expression in ileum, but not liver, and reduces ceramide levels and expression of various ceramide synthesis-related genes in ileum of mice with high-fat diet-induced obesity and db/db mice at 10 mg/kg; prevents weight gain, reduces blood glucose levels, and increases insulin sensitivity as well as prevents development of cholestasis and necrotic lesions in liver of mice with high-fat diet-induced obesity
保存温度:
-20
运输温度:
-20
预期分子量:
465.62276
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥95%
CAS号:
66225-78-3
分子式:
C26H43NO6
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