| 货号:40463-10 mg | 规格:10 mg | 目录价:¥2090 |
| 货号:40463-25 mg | 规格:25 mg | 目录价:¥4918 |
| 货号:40463-5 mg | 规格:5 mg | 目录价:¥1099 |
| 货号:40463-50 mg | 规格:50 mg | 目录价:¥8187 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
GMB 475
产品描述:
A PROTAC that drives Bcr-Abl degradation; induces degradation of Bcr-Abl (DC50 = 340 nM); selectively inhibits the proliferation of K562 and Bcr-Abl-expressing Ba/F3 cells (IC50 = ~1 µM for both) over parental Ba/F3 cells (IC50 = >10 µM); inhibits the proliferation of Ba/F3 cells expressing mutant Bcr-Abl (IC50s = 1.98 and 0.37 µM for Bcr-AblT315I and Bcr-AblG250E, respectively); induces apoptosis in primary human CML cells at 2.5 µM
保存温度:
-20
运输温度:
-20
预期分子量:
861.929529
产品形式:
A solid
纯度:
≥98%
CAS号:
2490599-18-1
分子式:
C43H46F3N7O7S
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