GNAS Antibody-多抗-深圳欣博盛生物科技有限公司

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GNAS Antibody

品牌：NSJ Bio

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说明书

折扣/货期

货号：F40026-0.08ML	规格：0.08 ml	目录价：￥2962.25
货号：F40026-0.4ML	规格：0.4 ml	目录价：￥6343.55

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

GNAS Antibody

产品描述:

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The Gs protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. Alternative splicing of downstream exons of the GNAS gene is observed, which results in different forms of the stimulatory G protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants have been found for this gene, but the full-length nature and/or biological validity of some variants have not been determined. Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors.

反应种属:

Human

宿主来源:

Rabbit

实验应用:

WB, IHC, IF, FACS, ELISA

同种型:

Rabbit Ig

免疫原:

A portion of amino acids 287-315 from the human protein was used as the immunogen for this GNAS antibody.

克隆性:

Polyclonal (rabbit origin)