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折扣/货期| 货号：RQ4782 | 规格：100 ul | 目录价：￥6488.05 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
GPR49 Antibody / LGR5
产品描述:
'G-protein coupled receptor 49,' or 'Leucine-rich repeat-containing G-protein coupled receptor 5' is a receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Involved in the development and/or maintenance of the adult intestinal stem cells during postembryonic development. [UniProt]
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB
同种型:
Rabbit IgG
免疫原:
A synthetic peptide specific to human GPR49 / LGR5 was used as the immunogen for the GPR49 antibody.
克隆性:
Rabbit Monoclonal
克隆号:
CHF-12
纯化方式:
Affinity purified
保存温度:
Store the GPR49 antibody at -20oC.
产品形式:
Purified
存储溶液:
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
产地:
美国
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