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折扣/货期| 货号：28733-10 mg | 规格：10 mg | 目录价：￥2157 |
| 货号：28733-25 mg | 规格：25 mg | 目录价：￥5065 |
| 货号：28733-5 mg | 规格：5 mg | 目录价：￥1380 |
| 货号：28733-50 mg | 规格：50 mg | 目录价：￥9407 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
GR113808
产品描述:
A 5-HT4 antagonist; binds to 5-HT4 receptors with an IC50 value of 0.4 nM in COS-7 cells expressing the human recombinant receptor and in guinea pig striatal membranes (IC50 = 0.5 nM); selective for 5-HT4 receptors over 5-HT1 receptors (Kis = >10 µM in dog saphenous vein and porcine vena cava), as well as 5-HT2 and 5-HT3 receptors (Kis = >10 and 1 μM in rabbit thoracic aorta and rat cerebral cortex, respectively); selective for 5-HT4 over adenosine, adrenergic, dopamine, GABA, muscarinic, nicotinic, histamine, and NMDA receptors (Kis = >10 μM for all); inhibits 5-HT-induced relaxation in carbachol-precontracted rat thoracic esophagus (pA2 = 9.3); inhibits 5-methoxytryptamine-induced tachycardia in anaesthetized piglets
保存温度:
-20
运输温度:
-20
预期分子量:
393.5015
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
144625-51-4
分子式:
C19H27N3O4S
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