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折扣/货期| 货号：40757-10 mg | 规格：10 mg | 目录价：￥1863 |
| 货号：40757-25 mg | 规格：25 mg | 目录价：￥3497 |
| 货号：40757-5 mg | 规格：5 mg | 目录价：￥1166 |
| 货号：40757-50 mg | 规格：50 mg | 目录价：￥6378 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
GS-444217
别名:
Apoptosis Signal-regulating Kinase 1 Inhibitor 1|Apoptosis Signal-regulating Kinase 1-IN-1|ASK1 Inhibitor 1|ASK1-IN-1
产品描述:
An AKS1 inhibitor (IC50 = 2.87 nM); selective for ASK1 over 442 additional kinases at 1 µM; inhibits phosphorylation of the ASK1 substrates MKK3, MKK6, and MKK4, as well as p38 MAPK and JNK in HEK293T cells expressing human ASK1 from 0.001-10 µM; reduces renal fibrosis and proteinuria in a db/db eNOS-/- mouse model of DKD at 0.3% w/w
保存温度:
-20
运输温度:
-20
预期分子量:
411.45942
产品形式:
A solid
纯度:
≥98%
CAS号:
1262041-49-5
分子式:
C23H21N7O
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