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折扣/货期| 货号：17489-1 mg | 规格：1 mg | 目录价：￥1112.2 |
| 货号：17489-10 mg | 规格：10 mg | 目录价：￥4984.8 |
| 货号：17489-25 mg | 规格：25 mg | 目录价：￥11055 |
| 货号：17489-5 mg | 规格：5 mg | 目录价：￥3323.2 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
GSK 199 (hydrochloride)
产品描述:
A PAD4 inhibitor (IC50 = 200 nM in the absence of calcium); selectively inhibits the production of citrulline by PAD4 over PAD1, PAD2, and PAD3 in kinetic assays; prevents ionomycin-induced histone H3 citrullination and NET formation in isolated mouse peripheral blood neutrophils at 10 µM; reduces HCoV-OC43 replication in infected MRC-5 cells (IC50 = 0.6 µM); reduces complement C3 deposition in the synovium and cartilage at 10 and 30 mg/kg and reduces disease severity at 30 mg/kg in a mouse model of collagen-induced arthritis; reduces plasma NET levels and brain infarct volume, as well as improves neurological outcomes, in a mouse model of tMCAO-induced ischemic stroke at 30 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
469
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
1549811-53-1
分子式:
C24H28N6O2 • HCl
促销活动
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