| 货号:28600 | 规格:1 mg | 目录价:¥1621.4 |
产品详情
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产品名称:
GSK2190915
别名:
AM803
产品描述:
A selective inhibitor of human FLAP (IC50 = 2.9 nM); selective for FLAP over 5-, 12-, and 15-lipoxygenase, LTA4 hydrolase, LTC4 synthase, COX-1, and COX-2 (IC50s = >10 µm for all); inhibits production of LTB4 induced by the calcium ionophore A23187 in isolated whole blood from human, rat, and mouse (IC50s = 436, 223, and 148 nM, respectively); decreases increases in the levels of CysLT and LTB4 induced by lung instillation of A23187 in the BALF of rats at 1 or 3 mg/kg; reduces increases in the levels of CysLT, LTB4, MPO, and plasma protein extravasation in a mouse model of peritonitis induced by zymosan at 3 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
637.83184
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
936350-00-4
分子式:
C38H43N3O4S
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