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折扣/货期| 货号：34886-1 mg | 规格：1 mg | 目录价：￥1139 |
| 货号：34886-10 mg | 规格：10 mg | 目录价：￥8884.2 |
| 货号：34886-5 mg | 规格：5 mg | 目录价：￥5011.6 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
GSK3368715 (hydrochloride)
产品描述:
An inhibitor of type I PRMTs (IC50s = 3.1, 162, 38, 4.7, and 39 nM for PRMT1, 3, 4, 6, and 8, respectively); selective for type I PRMTs over PRMT5, 7, and 9 (IC50s = >20,408, >40,000, and >15,000 nM, respectively), as well as 20 additional methyltransferases and a panel of ion channels, receptors, and transporters at 10 µM; inhibits the growth of patient-derived DLBCL cells at 5 µM; reduces tumor volume in Toledo and BxPC-3 mouse xenograft models from 9.375-150 mg/kg; reduces tumor growth in ACHN and MDA-MB-468 mouse xenograft models and a pancreatic adenocarcinoma PDX mouse model at 150 and 300 mg/kg, respectively
保存温度:
-20
运输温度:
-20
预期分子量:
403.00212
产品形式:
A solid
有效期:
1460
纯度:
≥98%
CAS号:
2227587-25-7
分子式:
C20H38N4O2 • HCl
促销活动
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