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折扣/货期| 货号：44360-1 mg | 规格：1 mg | 目录价：￥1112.2 |
| 货号：44360-10 mg | 规格：10 mg | 目录价：￥4984.8 |
| 货号：44360-25 mg | 规格：25 mg | 目录价：￥9674.8 |
| 货号：44360-5 mg | 规格：5 mg | 目录价：￥3323.2 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
GSK3685032
产品描述:
A DMNT1 inhibitor (IC50 = 0.23 µM); selective for DMNT1 over DMNT3A/3L and DMNT3B/3L and a panel of 34 methyltransferases and 369 kinases (IC50s = >10 µM for all); inhibits the proliferation of 51 hematological cancer cell lines (median IC50 = 0.64 µM); decreases overall DNA methylation and gene expression in MV4-11, THP-1, and NOMO-1 cells in a time- and concentration-dependent manner; increases the expression of genes encoding CXCL11, IFI27, and MAGEA4; reduces tumor volume and increases survival but does decrease blood numbers of neutrophils and red blood cells in SKM-1 and MV4-11 leukemia mouse xenograft models at 45, 30, or 15 mg/kg twice per day
保存温度:
-20
运输温度:
-20
预期分子量:
420.535
产品形式:
A solid
纯度:
≥98%
CAS号:
2170137-61-6
分子式:
C22H24N6OS
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