深圳欣博盛生物科技有限公司 a1

GSK5182
货号:19097-1 mg 规格:1 mg 目录价:¥670
货号:19097-10 mg 规格:10 mg 目录价:¥2653
货号:19097-25 mg 规格:25 mg 目录价:¥4985
货号:19097-5 mg 规格:5 mg 目录价:¥1501
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
GSK5182
产品描述:
An ERRγ inverse agonist (IC50 = 77 nM in a reporter assay); selectively binds to ERRγ over ERα, ERRα, and ERRβ (IC50s = 0.11, 2, >10, and >10 µM, respectively); enhances radioiodine uptake and NIS membrane localization in BHT-101 and CAL-62 anaplastic thyroid cancer cells; inhibits osteoclastogenesis induced by RANKL and M-CSF in primary mouse BMDMs and induces apoptosis in osteoclasts at 10 µM; inhibits ACEA-induced fibrinogen secretion in AML12 hepatocytes at 10 µM; decreases blood glucose levels in a pyruvate tolerance test in a mouse model of high-fat diet-induced obesity at 40 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
417.5
产品形式:
A solid
纯度:
≥95%
CAS号:
877387-37-6
分子式:
C27H31NO3
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