深圳欣博盛生物科技有限公司 a1

GSK547
货号:37347-1 mg 规格:1 mg 目录价:¥442
货号:37347-10 mg 规格:10 mg 目录价:¥2626
货号:37347-25 mg 规格:25 mg 目录价:¥4918
货号:37347-5 mg 规格:5 mg 目录价:¥1863
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
GSK547
别名:
RIP1i
产品描述:
A RIPK1 inhibitor (IC50 = 31 nM); selective for RIPK1 over a panel of 371 kinases at 10 µM; increases survival and reduces tumor volume and the number of liver metastases in a P48Cre KrasG12D orthotopic mouse model of progressive PDA at 100 mg/kg; adoptive transfer of tumor-infiltrating T cells isolated from GSK547-treated mice protects against orthotopic PDA tumor growth in mice; reduces plasma levels of TNF-α and IL-1β and decreases macrophage infiltration in aortic sinus lesions in an ApoESA/SA mouse model of early-phase atherogenesis
保存温度:
-20
运输温度:
-20
预期分子量:
396.393566
产品形式:
A solid
纯度:
≥98%
CAS号:
2226735-55-1
分子式:
C20H18F2N6O
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