| 货号:70785-1 mg | 规格:1 mg | 目录价:¥168 |
| 货号:70785-10 mg | 规格:10 mg | 目录价:¥1106 |
| 货号:70785-5 mg | 规格:5 mg | 目录价:¥630 |
| 货号:70785-50 mg | 规格:50 mg | 目录价:¥4774 |
| 货号:70785-25 mg | 规格:25 mg | 目录价:¥2632 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
GW 9662
产品描述:
The peroxisome proliferator-activated receptor γ (PPARγ) is the nuclear receptor responsible for transducing the therapeutic activity of the thiazolidinediones. Thiazolidinediones are a group of structurally related synthetic PPARγ agonists with antidiabetic actions in vivo. Rosiglitazone (BRL 49653) is a prototypical thiazolidinedione and has served as a reference compound for this class. There are many PPARγ agonists, including 15-deoxy-.DELTA.12,14-prostaglandin J2 and azelaoyl PAF, which are naturally derived. However, only a few antagonists have been reported. GW 9662 blocks the PPARγ-induced differentiation of monocytes to osteoclasts by >90% at a dose of 0.1 µM. It is therefore a much more potent antagonist than BADGE, which is another reported PPARγ antagonist.
保存温度:
-20
运输温度:
-20
预期分子量:
276.7
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
来源:
Synthetic
CAS号:
22978-25-2
分子式:
C13H9ClN2O3
促销活动
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