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折扣/货期| 货号：34418-10 mg | 规格：10 mg | 目录价：￥1956.4 |
| 货号：34418-25 mg | 规格：25 mg | 目录价：￥4623 |
| 货号：34418-50 mg | 规格：50 mg | 目录价：￥8227.6 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
GYKI 52466 (hydrochloride)
产品描述:
An allosteric AMPA receptor antagonist; selectively inhibits AMPA-induced inward currents (IC50 = 7.5 µM) over NMDA- or GABA-induced inward currents in primary rat hippocampal neurons at 50 µM but also inhibits kainate-induced inward currents in the same cells (IC50 = 11 µM); reduces the amplitude of spontaneous EPSCs in the same cells at 10 µM; increases the latency to seizure onset and reduces mortality in a rat model of 4-AP-induced generalized tonic-clonic seizures at 25 and 50 mg/kg; prevents neuronal damage in the CA1 region of the hippocampus in a four-vessel occlusion-induced rat model of global ischemia-reperfusion injury at 30 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
329.8
产品形式:
A solid
有效期:
1460
纯度:
≥98%
CAS号:
192065-56-8
分子式:
C17H15N3O2 • HCl
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