深圳欣博盛生物科技有限公司 a1

HAMI3379
货号:10580-1 mg 规格:1 mg 目录价:¥817
货号:10580-10 mg 规格:10 mg 目录价:¥6191
货号:10580-25 mg 规格:25 mg 目录价:¥13480
货号:10580-5 mg 规格:5 mg 目录价:¥3484
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
HAMI3379
产品描述:
A CysLT2 receptor antagonist (IC50 = 37.9 nM in a radioligand binding assay); selective for CysLT2 over CysLT1 (IC50 = >30 µM in a radioligand binding assay); inhibits LTD4- or LTC4-induced calcium mobilization in CHO cells expressing human CysLT2 (IC50s = 3.8 and 4.4 nM, respectively); reverses the LTC4-induced increases in perfusion pressure and decreases in contractility in isolated Langendorff-perfused guinea pig hearts; prevents decreases in body weight and neurological deficit scores in a rat model of S. pneumoniae-induced meningitis at 0.1 mg/kg; as well as reduces infarct volume in a rat model of MCAO-induced cerebral ischemia brain injury at 0.1 mg/kg; prevents increases in airway hyperresponsiveness in a mouse model of ovalbumin-induced asthma at 10 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
595.7
产品形式:
A crystalline solid
纯度:
≥90%
CAS号:
1245653-57-9
分子式:
C34H45NO8
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