| 货号:F41165-0.08ML | 规格:0.08 ml | 目录价:¥2962.25 |
| 货号:F41165-0.4ML | 规格:0.4 ml | 目录价:¥6343.55 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
HDAC6 Antibody
产品描述:
HDAC6 (histone deacetylase 6) is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. HDAC6 plays a central role in microtubule-dependent cell motility via deacetylation of tubulin, and has been shown to interact with HDAC11, SIRT2, and F-actin. HDAC6 is ubiquitinated, but its polyubiquitination however does not lead to degradation. HDAC is also a potential target of sumoylation.
反应种属:
Human, Mouse
宿主来源:
Rabbit
实验应用:
IHC, WB, ELISA
同种型:
Rabbit Ig
免疫原:
A portion of amino acids 1182-1215 from the human protein was used as the immunogen for this HDAC6 antibody.
克隆性:
Polyclonal (rabbit origin)
纯化方式:
Purified
保存温度:
Aliquot the HDAC6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Purified
存储溶液:
In 1X PBS, pH 7.4, with 0.09% sodium azide
产地:
美国
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