HER-2 Antibody-单抗-深圳欣博盛生物科技有限公司

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HER-2 Antibody

品牌：NSJ Bio

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说明书

折扣/货期

货号：F52968-0.08ML	规格：0.08 ml	目录价：￥2962
货号：F52968-0.4ML	规格：0.4 ml	目录价：￥6344

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

HER-2 Antibody

产品描述:

Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. This prevents the phosphorylation of APC and CLASP2, allowing its association with the cell membrane. In turn, membrane-bound APC allows the localization of MACF1 to the cell membrane, which is required for microtubule capture and stabilization.

反应种属:

Human

宿主来源:

Mouse

实验应用:

WB, ELISA

同种型:

Mouse IgG2b, k

免疫原:

This HER-2 antibody was produced from a mouse immunized with a recombinant protein.

克隆性:

Monoclonal (mouse origin)