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折扣/货期| 货号：24199-1 mg | 规格：1 mg | 目录价：￥724 |
| 货号：24199-10 mg | 规格：10 mg | 目录价：￥4569 |
| 货号：24199-25 mg | 规格：25 mg | 目录价：￥10492 |
| 货号：24199-5 mg | 规格：5 mg | 目录价：￥2988 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Hesperadin
产品描述:
A multi-kinase inhibitor; inhibits human Aurora kinase B (IC50 = 250 nM) and the T. brucei homolog Aurora kinase-1 (IC50 = 40 nM); inhibits AMPK, LCK, MKK1, MAPKAP-K1, CHK1, and PHK in a panel of 25 kinases at 1 µM; inhibits MEKK2 in ATPase and transphosphorylation assays (IC50s = 60 and 34 nM, respectively); induces polyploidy and defects in cytokinesis and spindle assembly as well as inhibits proliferation of HeLa cells and overrides paclitaxel- and monastrol-induced mitotic arrest from 50-100 nM; induces toxicity in HepG2 cells (TC50 = 50 = 0.22-2.21 µM); inhibits the growth of T. brucei, L. major promastigotes and amasigotes, and P. falciparum (EC50s = 0.01-2.37 µM)
保存温度:
-20
运输温度:
-20
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
422513-13-1
分子式:
C29H32N4O3S
促销活动
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